Fushi Wen

Title: Fushi Wen: Innovator in RNA Detection Technologies

Introduction

Fushi Wen is a prominent inventor based in Tucson, AZ, known for his significant contributions to the field of RNA detection technologies. With a total of 3 patents, he has made strides in developing methods that enhance the detection of pathogenic viruses, including COVID-19.

Latest Patents

Fushi Wen's latest patents include innovative methods for RNA detection. One notable patent is for "Transcription mediated amplification methods for RNA detection." This method allows for the detection of COVID-19 virus RNA and other pathogenic respiratory viruses by obtaining nucleic acids from a sample. The process involves a combined isothermal reverse transcription, RNAse H, and isothermal amplification reaction to generate single-stranded RNA amplicons. These amplicons hybridize with fluorescent labeled detector probes, enabling the identification of the virus through imaging of fluorescent signals.

Another significant patent is the "Combinatorial microarray assay for clade variant detection." This method focuses on detecting clade variants of the COVID-19 virus in human and environmental samples. Total RNA is processed and used as a template in a reverse transcription and amplification reaction to obtain fluorescent COVID-19 virus amplicons. These amplicons are then hybridized on a microarray with nucleic acid probes that can distinguish among various clade variants, allowing for precise identification through unique intensity distribution profiles.

Career Highlights

Fushi Wen is currently associated with Pathogendx, Inc., where he continues to innovate in the field of molecular diagnostics. His work has been instrumental in developing technologies that address urgent public health challenges.

Collaborations

Fushi Wen collaborates with notable colleagues, including Frederick Henry Eggers and Benjamin Alan Katchman, who contribute to the advancement of his research and innovations.

Conclusion

Fushi Wen's contributions to RNA detection technologies are vital in the ongoing fight against viral infections. His innovative patents and collaborative efforts position him as a key figure in the field of molecular diagnostics.