Frank Verdonck

Title: Frank Verdonck: Innovator in Immunology

Introduction

Frank Verdonck is a notable inventor based in Sint-Gillis-Waas, Belgium. He has made significant contributions to the field of immunology, particularly through his innovative work on single variable domain antibodies. With a total of 3 patents to his name, Verdonck is recognized for his advancements in therapeutic applications.

Latest Patents

One of Verdonck's latest patents focuses on single variable domain antibodies against OX40L. This invention relates to immunoglobulin single variable domain sequences that are directed against OX40L. The patent describes compounds or constructs, particularly proteins and polypeptides, that comprise or essentially consist of these immunoglobulin single variable domain sequences. These sequences can block the binding of OX40L to OX40, which is crucial for therapeutic applications. The immunoglobulin single variable domains, compounds, and constructs can be utilized for prophylactic, therapeutic, or diagnostic purposes. They are particularly relevant for treating inflammatory diseases and disorders such as asthma, allergic asthma, chronic colitis, Crohn's disease, inflammatory bowel disease, and arthrosclerosis.

Career Highlights

Frank Verdonck is currently associated with Ablynx N.V., a company known for its innovative approaches in biopharmaceuticals. His work has significantly impacted the development of new therapeutic strategies in immunology.

Collaborations

Throughout his career, Verdonck has collaborated with notable colleagues, including Sigrid Cornelis and Stephanie Staelens. These collaborations have further enhanced his research and development efforts in the field.

Conclusion

Frank Verdonck is a distinguished inventor whose work in immunology has led to important advancements in therapeutic applications. His contributions continue to influence the treatment of various inflammatory diseases.