Frank R Holden

Title: Frank R. Holden: Innovator in Combinatorial Library Evaluation

Introduction

Frank R. Holden is a notable inventor based in Belmont, CA (US). He has made significant contributions to the field of combinatorial chemistry, particularly in the evaluation of compound libraries. His innovative approach has led to the development of a patented device that enhances the quality assessment of these libraries.

Latest Patents

Frank R. Holden holds a patent for an "Apparatus and methods for evaluating the quality of a combinatorial library of compounds." This invention provides devices and methods that facilitate the evaluation of the quality of a combinatorial library. One exemplary device comprises a holding plate with an array of apertures, where a plurality of vials is removably held. Each vial has an open top end, and a seal member is placed over the top ends of the vials. A top plate is then removably coupled to the holding plate to force the seal member against the top ends of the vials. This innovative design allows for more efficient and accurate evaluations of compound libraries.

Career Highlights

Throughout his career, Frank R. Holden has been associated with Glaxo Wellcome Inc., where he has contributed to various projects and innovations. His work has been instrumental in advancing the methodologies used in combinatorial chemistry.

Collaborations

Frank has collaborated with notable colleagues, including William L. Fitch and Kenneth C. Lewis. These collaborations have further enriched his work and contributed to the success of his inventions.

Conclusion

Frank R. Holden is a distinguished inventor whose work in evaluating combinatorial libraries has made a significant impact in the field. His patented device exemplifies innovation and efficiency in compound evaluation.