Frank N Chang, Administrator

Title: Frank N. Chang: Innovator in Protein Production and Purification

Introduction

Frank N. Chang is a notable inventor and administrator based in Dresher, PA (US). He has made significant contributions to the field of biotechnology, particularly in the production and purification of hybrid polypeptides. His innovative approach utilizes recombinant DNA techniques to enhance the efficiency of protein production.

Latest Patents

Frank N. Chang holds a patent for the "Production and purification of a protein fused to a binding protein." This patent outlines methods and products for producing and purifying hybrid polypeptide molecules. The process involves fusing a DNA fragment coding for a protein molecule with a DNA fragment coding for a binding protein, such as maltose binding protein. The fused DNA is then inserted into a cloning vector and transformed into an appropriate host. Upon expression, a hybrid polypeptide is produced, which can be purified using affinity chromatography. This invention has broad applications in biotechnology and protein engineering.

Career Highlights

Throughout his career, Frank N. Chang has worked with reputable organizations, including New England Biolabs, Inc. and Temple University. His experience in these institutions has allowed him to develop and refine his innovative techniques in protein production.

Collaborations

Frank N. Chang has collaborated with notable individuals in his field, including Chudi Guan and the late Hiroshi Inouye. These collaborations have contributed to advancements in biotechnology and have fostered a spirit of innovation.

Conclusion

Frank N. Chang's contributions to the field of protein production and purification exemplify the impact of innovative thinking in biotechnology. His patent and career achievements highlight the importance of collaboration and research in advancing scientific knowledge.