Company Filing History:
Years Active: 1997-1998
Title: Frank Costantini: Innovator in Molecular Biology
Introduction
Frank Costantini is a prominent inventor based in New York, NY (US), known for his significant contributions to molecular biology. He holds 2 patents that focus on the development of innovative methods and compositions related to viral receptors.
Latest Patents
His latest patents include groundbreaking work on the molecular cloning of genomic and cDNA sequences encoding cellular receptors for picornavirus. The first patent provides an isolated nucleic acid molecule that encodes a polypeptide with the biological activity of a receptor for picornavirus. This invention also outlines a method utilizing expression vectors in a host vector system to induce the production of a picornavirus receptor. The second patent details a transgenic mouse expressing DNA sequences that encode the human poliovirus receptor. This invention includes a purified polypeptide with the same activity and methods for producing transgenic animals that express these receptors. Additionally, it offers therapeutic compositions for treating and preventing human poliovirus infections.
Career Highlights
Frank Costantini is affiliated with Columbia University, where he has made significant strides in his research. His work has contributed to the understanding of viral infections and the development of potential treatments.
Collaborations
He has collaborated with notable colleagues, including Vincent Racaniello and Cathy Mendelsohn, enhancing the impact of his research through teamwork and shared expertise.
Conclusion
Frank Costantini's innovative work in molecular biology has led to important advancements in the understanding and treatment of viral infections. His contributions continue to influence the field and pave the way for future research.