Frank Balis

Title: The Innovations of Frank Balis

Introduction

Frank Balis is an accomplished inventor based in Bethesda, MD (US). He holds three patents that showcase his contributions to the field of biochemistry and molecular biology. His work primarily focuses on the development of fluorescent nucleotides, which have significant applications in DNA amplification and oligonucleotide synthesis.

Latest Patents

One of his notable patents is for pteridine nucleotide analogs. This invention provides pteridine nucleotides that are highly fluorescent and can be utilized in the chemical synthesis of fluorescent oligonucleotides. The invention also includes fluorescent oligonucleotides comprising one or more pteridine nucleotides. Additionally, it offers pteridine nucleotide triphosphates that may serve as constituent monomers in DNA amplification procedures. These pteridine nucleotides are recognized for their stability and higher quantum yields compared to structurally similar compounds. Another significant patent by Balis is for pteridine nucleotide analogs as fluorescent DNA probes. This invention presents novel pteridine nucleotides that exhibit high fluorescence under physiological conditions, further enhancing their utility in the synthesis of fluorescent oligonucleotides.

Career Highlights

Throughout his career, Frank Balis has worked with esteemed organizations, including the United States of America as represented by the Secretary of Health and the Department of Health. His innovative work has contributed to advancements in the field of molecular biology.

Collaborations

Frank Balis has collaborated with notable individuals such as Mary E Hawkins and Wolfgang Pfleiderer. These collaborations have likely enriched his research and development efforts.

Conclusion

Frank Balis is a prominent inventor whose work in developing fluorescent nucleotides has made a significant impact in the field of biochemistry. His patents reflect his dedication to advancing scientific knowledge and technology.