Frank A Sinicrope

Title: Frank A. Sinicrope: Innovator in Colorectal Cancer Evaluation

Introduction

Frank A. Sinicrope is a notable inventor based in Rochester, MN (US). He has made significant contributions to the field of cancer research, particularly in the evaluation of immune cell infiltrate in stage III colorectal cancer. His innovative work has the potential to enhance diagnostic and treatment decisions for patients suffering from this disease.

Latest Patents

Frank A. Sinicrope holds a patent for "Methods and systems for evaluation of immune cell infiltrate in stage III colorectal cancer." This patent describes a process where immune context scores are calculated for stage III colorectal tumor tissue samples using continuous scoring functions. Feature metrics for at least one immune cell marker are calculated for specific regions of interest, including the density of human CD3+ cells in the invasive margin. A continuous scoring function is then applied to a feature vector, resulting in an immune context score. This score can be plotted against various diagnostic or treatment metrics, aiding in prognostic and predictive assessments. Ultimately, the immune context score can be integrated into diagnostic and treatment decisions.

Career Highlights

Throughout his career, Frank A. Sinicrope has worked with prominent organizations such as Ventana Medical Systems, Inc. and the Mayo Foundation for Medical Education and Research. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

One of his notable collaborators is Kandavel Shanmugam. Their partnership has likely fostered innovative approaches to cancer research and treatment.

Conclusion

Frank A. Sinicrope's contributions to the evaluation of immune cell infiltrate in colorectal cancer exemplify the impact of innovation in medical research. His work not only advances scientific understanding but also holds promise for improving patient outcomes.