Franco Tzul

Title: The Innovations of Franco Tzul

Introduction

Franco Tzul is a notable inventor based in Hartsdale, NY (US). He has made significant contributions to the field of pharmaceuticals, particularly in the area of lyophilization and viral vector characterization. With a total of 5 patents to his name, Tzul's work has advanced the understanding and application of drug formulation and delivery.

Latest Patents

Franco Tzul's latest patents include innovative methods for lyophilizing drug products. One of his patents focuses on achieving a target residual moisture content for lyophilized drug products. This method allows for improved stability of protein formulations during long-term storage at room temperature or refrigeration. Specifically, Tzul's application provides techniques to obtain a target percentage of residual moisture, such as 3-5%. The secondary drying process can be controlled to match the shelf temperature of the primary drying, or it can be conducted without a distinct secondary drying step.

Another significant patent involves the characterization of adeno-associated virus using microchip capillary electrophoresis. This patent outlines methods for identifying capsid viral proteins in samples containing viral vectors. The process includes denaturing the capsid viral proteins, labeling them with a lysine-conjugation dye, and generating a separation profile using microchip capillary electrophoresis. Tzul's methods allow for quantifying levels of capsid viral proteins and determining their ratios based on the separation profile.

Career Highlights

Franco Tzul has worked with prominent companies in the pharmaceutical industry, including Regeneron Pharmaceuticals, Inc. and Regeneran Pharmaceuticals, Inc. His experience in these organizations has contributed to his expertise in drug formulation and development.

Collaborations

Throughout his career, Tzul has collaborated with talented individuals such as Xiaolin Tang and Mary Kleppe. These partnerships have fostered innovation and have led to advancements in the field of pharmaceuticals.

Conclusion

Franco Tzul's contributions to the pharmaceutical industry through his patents and collaborations highlight his role as an influential inventor. His work continues to impact drug formulation and delivery, showcasing the importance of innovation in healthcare.