Company Filing History:
Years Active: 1999
Title: Franco Di Padova: Innovator in Monoclonal Antibody Development
Introduction
Franco Di Padova is a notable inventor based in Birsfelden, Switzerland. He has made significant contributions to the field of immunology, particularly in the development of monoclonal antibodies. His work focuses on addressing endotoxemia caused by Gram-negative bacterial strains.
Latest Patents
Franco Di Padova holds a patent for a monoclonal antibody against LPS core. This invention provides monoclonal antibodies (Mabs) that are cross-protective against endotoxemia caused by at least two different Gram-negative bacterial strains with varying core structures. The methods of production for these antibodies involve the Kohler/Milstein procedure, which includes immunizing mice with different rough strains of heat-killed Gram-negative bacteria, followed by fusion and screening of the resulting hybridomas. The murine MAbs can be chimerized or humanized using established methods.
Career Highlights
Franco Di Padova is associated with the Common Services Agency, where he applies his expertise in antibody development. His innovative approach has led to advancements in the production of chimeric monoclonal antibodies, which are crucial for therapeutic applications.
Collaborations
Franco has collaborated with esteemed colleagues such as Hermann Gram and George Robin Barclay. Their combined efforts have contributed to the progress in the field of immunology and the development of effective treatments.
Conclusion
Franco Di Padova's work in monoclonal antibody development showcases his dedication to advancing medical science. His innovative contributions have the potential to significantly impact the treatment of bacterial infections.