Francisco Carrio Fontsere

Title: Innovations of Francisco Carrio Fontsere

Introduction

Francisco Carrio Fontsere is a notable inventor based in Parsippany, NJ (US). He has made significant contributions to the field of chemistry, particularly in the development of anti-inflammatory agents. With a total of 2 patents, his work showcases a commitment to advancing pharmaceutical processes.

Latest Patents

Carrio Fontsere's latest patents focus on an improved process for the preparation of 4-hydroxy-3-(5-methyl-3-isoxazolylcarbamoyl)-2-methyl-2H-1,2-benzothiazine 1,1-dioxide, a known anti-inflammatory agent. The process involves the reaction of alkyl 2,3-dihydro-3-oxo-1,2-benzisothiazole-2-acetate in dimethylformamide with an alkali metal alkoxide. This method emphasizes the importance of specific proportions of reactants and carefully controlled reaction conditions. The acidification of the reaction mixture leads to the precipitation of alkyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate in high yields, without the need for recrystallization. Furthermore, the process has been refined to enhance the purification of the crude product, eliminating the need for large quantities of dioxane solvent.

Career Highlights

Carrio Fontsere is currently associated with Warner-Lambert Company, where he continues to innovate in the pharmaceutical sector. His work has not only contributed to the development of anti-inflammatory agents but also holds potential for the preparation of other useful benzothiazine derivatives.

Collaborations

One of his notable collaborators is Jerome D Genzer, with whom he has worked on various projects aimed at improving chemical processes.

Conclusion

Francisco Carrio Fontsere's contributions to the field of chemistry, particularly in the development of anti-inflammatory agents, highlight his innovative spirit and dedication to advancing pharmaceutical science. His work continues to impact the industry positively.