Company Filing History:
6 out of 1,942 
1 out of 894 
1 out of 832,912 Years Active: 1998-2013
Title: Francis X Cunningham, Jr: Pioneer in Carotenoid Biochemistry
Introduction
Francis X Cunningham, Jr, based in Chevy Chase, Maryland, is a distinguished inventor known for his significant contributions to the field of biochemistry. With a portfolio of 7 patents, he has made pivotal advancements in the study and production of carotenoids, particularly astaxanthin.
Latest Patents
Cunningham's latest patents focus on innovative biochemical processes. One notable patent details a method for a biochemical route to astaxanthin, disclosing two nucleic acid sequences isolated from a cDNA library of flowering plants. The first DNA sequence, AdKC28, encodes a polypeptide that interacts with polypeptides from two closely-related cDNAs, AdKeto1 and AdKeto2, to convert β-carotene into astaxanthin. Additionally, a second DNA sequence, AdKCl 7, is included. These sequences, once linked to appropriate promoters in transgenic hosts, facilitate the production of astaxanthin and other carotenoids. Another patent encompasses methods for producing carotenoids through the expression of plant β-cyclase genes, offering nucleic acid sequences and vectors for transforming hosts. This innovation also provides techniques for controlling the carotenoid ratios and offers a method for screening eukaryotic genes related to carotenoid biosynthesis, which may lead to the modification of enzymes involved in this process.
Career Highlights
Cunningham's career is marked by his association with reputable institutions, including the University of Maryland and Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. His work has positioned him as a vital contributor to the field of carotenoid research, fostering advancements in biotechnology.
Collaborations
During his career, Cunningham collaborated with esteemed colleagues such as Zairen Sun and Joseph Hirschberg. These partnerships have been instrumental in broadening the scope of his research and enhancing the impact of his inventions in the field of biochemistry.
Conclusion
Francis X Cunningham, Jr's innovative work in biochemistry, particularly in the production and modification of carotenoids, exemplifies the crucial role of inventors in advancing scientific understanding and technology. His contributions continue to influence research and applications in the field, showcasing the importance of collaboration and ingenuity in driving innovation forward.