Location History:
- Park, PA (US) (2006)
- Philadelphia, PA (US) (1993 - 2010)
- Phila, PA (US) (2013)
Company Filing History:
Years Active: 1993-2013
Title: The Innovative Contributions of Francis Kappler
Introduction
Francis Kappler is a notable inventor based in Philadelphia, PA, who has made significant contributions to the field of biochemistry and therapeutic methods. With a total of seven patents to his name, Kappler's work focuses on addressing the deleterious effects of certain compounds in the body, particularly those related to skin health.
Latest Patents
Among his latest patents, one notable invention is a method for alleviating the harmful effects of 3-deoxyglucosone. This patent discloses a class of compounds that inhibit the enzymatic conversion of fructose-lysine into fructose-lysine-3-phosphate in an ATP-dependent reaction. The normal functioning of this metabolic pathway involves the breakdown of fructose-lysine-3-phosphate to form free lysine, inorganic phosphate, and 3-deoxyglucosone, which is a reactive protein-modifying agent. Kappler's invention also includes therapeutic methods for using these inhibitors to mitigate the adverse effects of 3-deoxyglucosone. Another significant patent relates to a method of removing 3-deoxyglucosone and other alpha-dicarbonyl sugars from the skin, as well as methods for inhibiting their production and function in skin-related diseases and disorders.
Career Highlights
Throughout his career, Francis Kappler has worked with esteemed organizations such as Fox Chase Cancer Center and Dynamis Therapeutics, Inc. His work in these institutions has allowed him to further his research and develop innovative solutions to complex health issues.
Collaborations
Kappler has collaborated with notable colleagues, including Truman R. Brown and Annette Tobia, contributing to a rich exchange of ideas and advancements in their respective fields.
Conclusion
Francis Kappler's innovative work and patents have made a significant impact in the realm of biochemistry and therapeutic methods. His dedication to alleviating health issues related to 3-deoxyglucosone showcases his commitment to improving human health through scientific innovation.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.