Company Filing History:
Years Active: 1989-1990
Title: Frances M Yeager: Innovator in Hemoglobin Analysis
Introduction
Frances M Yeager is a notable inventor based in Middlebury, IN (US). She has made significant contributions to the field of analytical methods for determining hemoglobin derivatives in blood samples. With a total of 2 patents, her work has advanced the reliability and efficiency of hemoglobin analysis.
Latest Patents
Yeager's latest patents include innovative methods for hemoglobin determination. One patent focuses on denaturant reagents for convenient determination of hemoglobin. This analytical method allows for the measurement of both total hemoglobin and specific hemoglobin derivatives, such as glycated hemoglobin, in a blood sample. The process involves treating the blood sample with a combination of a thiocyanate salt and an oxidant, which denatures the hemoglobin and converts it to met-hemoglobin. This method enhances the assay's reliability and reduces overall determination time.
Another patent involves a latex agglutination immunoassay method for determining analytes in blood samples. This method maintains the pH of the reaction mixture at about 8.5 or greater to prevent nonspecific agglutination of latex particles by hemoglobin. It is particularly useful for determining glycated hemoglobin, such as Hb Alc. Additionally, it allows for the determination of native hemoglobin based on its agglutination properties in a lower pH environment.
Career Highlights
Frances M Yeager has worked at Miles Inc., where she has applied her expertise in hemoglobin analysis. Her innovative approaches have contributed to advancements in medical diagnostics and analytical chemistry.
Collaborations
Yeager has collaborated with notable coworkers, including Lowry J Messenger and Kin F Yip. These collaborations have further enriched her research and development efforts in the field.
Conclusion
Frances M Yeager's contributions to hemoglobin analysis through her patents have significantly impacted the field of medical diagnostics. Her innovative methods enhance the accuracy and efficiency of hemoglobin determination, showcasing her role as a leading inventor in this area.
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