Company Filing History:
Years Active: 1995-1997
Title: Flavio Toma: Innovator in Peptide Derivatives
Introduction
Flavio Toma is a notable inventor based in Clamart, France. He has made significant contributions to the field of medicinal chemistry, particularly in the development of peptide derivatives. With a total of 3 patents to his name, Toma's work focuses on innovative solutions for medical applications.
Latest Patents
Toma's latest patents include the use of peptide derivatives for the preparation of medicaments that inhibit endopeptidases 24.15 and 24.16. This invention involves peptide derivatives that follow a specific formula, where R¹ is an optionally substituted aralkyl group, R² is Pro, Hyp, thiazolidine, or dehydroproline, and R³ is H or an alkyl radical. Notable examples of effective derivatives include N-(phenylethylphosphonyl)-Gly-Pro-aminohexanoic acid and N-(phenylethyl phosphonyl)-Ala-Pro-aminohexanoic acid. Another significant patent involves novel peptide derivatives that serve as inhibitors of bacterial collagenases. These derivatives comply with a specific formula, where R¹ can be a hydrogen atom or a radical derived from an amino acid, and R² represents the side chain of an α-amino acid.
Career Highlights
Flavio Toma is currently associated with the Commissariat à l'Énergie Atomique, where he continues to advance his research in peptide chemistry. His work has garnered attention for its potential applications in medical treatments and therapeutic interventions.
Collaborations
Toma has collaborated with esteemed colleagues such as Vincent Dive and Athanasios Yiotakis, contributing to a rich exchange of ideas and innovations in their field.
Conclusion
Flavio Toma's contributions to the field of peptide derivatives highlight his innovative spirit and dedication to advancing medical science. His patents reflect a commitment to developing effective solutions for complex medical challenges.