This inventor holds 1 USPTO granted patent. Top assignee: The University of Texas System. Active years: 1999.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1999
Title: Flavia M Bazzoni: Innovator in Engineered Cell Surface Receptors
Introduction
Flavia M Bazzoni is a prominent inventor based in Dallas, TX (US). She has made significant contributions to the field of biotechnology, particularly in the development of engineered cell surface receptors. Her innovative work has the potential to impact various therapeutic applications.
Latest Patents
Flavia M Bazzoni holds 1 patent for her invention titled "Modified receptors that continuously signal." This patent describes engineered cell surface receptors that are constitutively active in the absence of the cytokine, hormone, or molecule that typically activates the receptor. The invention involves creating receptors that signal continuously by engineering them to form multimers at the cell surface. The patent discloses various DNA, protein, and cellular compositions, along with methods for making and using these constitutively active receptors. Notably, the invention includes fusion proteins where the stem, transmembrane domain, and cytoplasmic domain are derived from a TNF receptor, while the extracellular, multimerizing domain comes from an erythropoietin receptor. Transfection of these fusion protein constructs into cells has demonstrated a strong cytotoxic effect.
Career Highlights
Flavia M Bazzoni is affiliated with the University of Texas System, where she continues her research and development in the field of biotechnology. Her work has garnered attention for its innovative approach to receptor engineering and its potential applications in medicine.
Collaborations
Flavia has collaborated with notable scientists, including Bruce A Beutler, to advance her research and explore new avenues in the field of engineered receptors.
Conclusion
Flavia M Bazzoni's contributions to the field of biotechnology through her innovative patents and collaborations highlight her role as a leading inventor. Her work on engineered cell surface receptors is paving the way for future advancements in therapeutic applications.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile