Company Filing History:
Years Active: 2023
Title: Fidan Erden Karaoglan: Innovator in Synthetic Promoter Design
Introduction
Fidan Erden Karaoglan is a prominent inventor based in Erzincan, Turkey. She has made significant contributions to the field of biotechnology, particularly in the design of synthetic promoters for recombinant protein production. Her innovative work has led to the development of a patent that enhances our understanding of regulatory DNA regions.
Latest Patents
Karaoglan holds a patent titled "Determination of regulatory DNA regions of alcohol dehydrogenase 3 (ADH3) promoter and design of synthetic promoters for recombinant protein production." This invention focuses on the ADH3 promoter and includes polynucleotide sequences, vectors, and expression cassettes that contain DNA regions responsible for regulating the ADH3 promoter. The research involved deletion analyses in the ADH3 promoter to identify regions that influence promoter strength. Notably, the deletion of nucleotides between 539 and 638 resulted in a remarkable 63% increase in ADH3 promoter activity. Furthermore, five different synthetic promoters were created using identified positive regulatory regions, achieving promoter activities ranging from approximately 165% to 200%.
Career Highlights
Karaoglan is affiliated with Akdeniz Universitesi, where she continues her research and development in the field of biotechnology. Her work not only contributes to academic knowledge but also has practical applications in the production of recombinant proteins.
Collaborations
Karaoglan collaborates with notable colleagues, including Mehmet Inan and Mert Karaoglan, to advance her research initiatives. Their combined expertise enhances the quality and impact of their work in the field.
Conclusion
Fidan Erden Karaoglan is a trailblazer in the field of synthetic biology, with her innovative patent paving the way for advancements in recombinant protein production. Her contributions are vital to the ongoing research and development in biotechnology.