Company Filing History:
2 out of 261 
1 out of 1,732 
Years Active: 1993-1995
Title: The Innovative Contributions of Feng Gao
Introduction
Feng Gao is a notable inventor based in Tempe, Arizona, recognized for his significant contributions to the field of anticancer drug research. With a total of three patents to his name, Gao has focused on the isolation and structural elucidation of novel compounds derived from marine organisms.
Latest Patents
Gao's latest patents include the isolation and structure of Halistatin 1 and Halistatin 2. Halistatin 1 was isolated from the Western Indian Ocean sponge Phakellia carteri. This new polyether macrolide demonstrated a yield of 8.8 x 10^-7 % and was found to cause the accumulation of cells arrested in mitosis, inhibit tubulin polymerization, and hinder the binding of radiolabeled vinblastine and GTP to tubulin. Similarly, Halistatin 2, isolated from the sponge Axinella cf. carteri, exhibited a yield of 1.4 x 10^-6 %. This compound also caused cell accumulation in mitosis and displayed significant activity against selected human tumor cell lines.
Career Highlights
Throughout his career, Feng Gao has worked with various institutions, including the Arizona Board of Regents and Arizona State University. His research has been pivotal in exploring new sources for anticancer drugs, contributing to the scientific community's understanding of marine-derived compounds.
Collaborations
Gao has collaborated with notable individuals in his field, including George R. Pettit and Rui Tan. Their collective efforts have advanced the research and development of innovative anticancer therapies.
Conclusion
Feng Gao's work exemplifies the intersection of marine biology and medicinal chemistry, showcasing the potential of natural compounds in the fight against cancer. His patents and research contributions continue to inspire advancements in drug discovery.