This inventor holds 3 USPTO granted patents. Top assignees: The University of Alabama, Other. Active years: 1995-1998.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1995-1998
Title: Fardos N Naguib: Innovator in Enzyme Inhibitors and Cancer Therapy
Introduction
Fardos N Naguib is a prominent inventor based in Mountain Brook, AL (US). She has made significant contributions to the field of biochemistry, particularly in the development of enzyme inhibitors and methods for optimizing cancer therapy. With a total of 3 patents, her work has the potential to impact pharmaceutical treatments and improve patient outcomes.
Latest Patents
Naguib's latest patents include innovative compounds that effectively inhibit the activity of DHUDase or UrdPase. These compounds have a general formula where X is S or Se, and Y can be various elements or groups such as I, F, Cl, Br, methoxy, benzyl, selenenylphenyl, or thiophenyl. The compounds can be utilized in pharmaceutical compositions alongside chemotherapeutic agents to enhance treatment efficacy. Additionally, they can be administered to prevent and treat disorders related to pyrimidine catabolism and other physiological disorders. Another significant patent involves methods for predicting intolerance to fluoropyrimidines by measuring orotate phosphoribosyltransferase activity in biological samples. This method aids in determining a non-toxic dose of 5-fluorouracil for individuals undergoing fluoropyrimidine therapy.
Career Highlights
Throughout her career, Naguib has worked with notable institutions, including the University of Alabama. Her research has focused on the synthesis of novel compounds and their applications in treating various diseases, including cancers and infections.
Collaborations
Naguib has collaborated with esteemed colleagues such as Mahmoud H El Kouni and Raymond F Schinazi. These partnerships have contributed to the advancement of her research and the development of her patented inventions.
Conclusion
Fardos N Naguib's innovative work in enzyme inhibitors and cancer therapy showcases her dedication to improving medical treatments. Her patents reflect her commitment to advancing biochemistry and enhancing patient care.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile