Location History:
- Chelmsford, MA (US) (2000)
- Billerica, MA (US) (2001 - 2009)
Company Filing History:
2 out of 2 
2 out of 1,036 
Years Active: 2000-2009
Title: Falguni M Kher: Innovator in Chemical Compounds for Medical Applications
Introduction
Falguni M Kher is a notable inventor based in Billerica, MA (US), recognized for her contributions to the field of chemical compounds aimed at treating various medical conditions. With a total of three patents to her name, she has made significant strides in developing innovative solutions for diseases characterized by unwanted cellular proliferation.
Latest Patents
Her latest patents focus on the use of triaryl methane compounds for inhibiting unwanted cellular proliferation associated with inflammatory diseases. The inventions provide a class of chemical compounds that serve as efficacious drugs in the treatment of sickle cell disease and other conditions marked by abnormal cell proliferation. The active compounds are substituted triaryl methane compounds or analogues, where one or more of the aryl groups is replaced with a heteroaryl, cycloalkyl, or heterocycloalkyl group. Additionally, the tertiary carbon atom can be replaced with different atoms such as silicon, germanium, nitrogen, or phosphorus. These compounds are designed to inhibit mammalian cell proliferation, block the Gardos channel of erythrocytes, reduce sickle erythrocyte dehydration, and delay the occurrence of erythrocyte sickling or deformation.
Career Highlights
Falguni has worked with reputable organizations such as Ion Pharmaceuticals, Inc. and Children's Medical Center Corporation. Her work in these institutions has allowed her to further her research and development in the field of medical chemistry.
Collaborations
Throughout her career, Falguni has collaborated with esteemed colleagues, including Carlo Brugnara and Jose Alberto Halperin. These partnerships have contributed to her innovative research and the advancement of her patented technologies.
Conclusion
Falguni M Kher's work in developing triaryl methane compounds represents a significant advancement in the treatment of inflammatory diseases and sickle cell disease. Her contributions to medical chemistry continue to pave the way for innovative therapeutic solutions.