Company Filing History:
Years Active: 1995
Title: Innovations by Fabrizio Ungarelli
Introduction
Fabrizio Ungarelli is a notable inventor based in Bologna, Italy. He has made significant contributions to the field of glycosaminoglycans, particularly in the development of new heparin and heparan sulfate derivatives. With a total of 3 patents, his work focuses on enhancing the biological properties of these compounds.
Latest Patents
Ungarelli's latest patents include innovations related to semi-synthetic glycosaminoglycans with heparin or heparan structures. One of his key inventions involves the creation of new heparin and heparan sulfate derivatives that possess antithrombotic activity while reducing hemorrhagic and anticoagulant effects. This is achieved through nucleophilic addition to heparin and heparan sulfate derivatives containing 2,3-anhydrogulonic acid residues. The resulting glycosaminoglycan derivatives exhibit structural modifications that improve their biological properties, maintaining antithrombotic activity while diminishing adverse effects.
Another significant patent details a process for synthesizing glycosaminoglycans. In this process, one of the α-L-iduronic-2-O-sulfate acid saccharide units undergoes structural modification, transforming into α-L-galacturonic acid substituted with nucleophilic groups. This innovative synthesis is conducted by treating glycosaminoglycans with heparin or heparan structures using a nucleophilic reagent in an alkaline solution.
Career Highlights
Fabrizio Ungarelli has worked with prominent companies such as Alfa Wassermann S.p.A. His experience in the pharmaceutical industry has allowed him to focus on the development of advanced therapeutic compounds.
Collaborations
Throughout his career, Ungarelli has collaborated with notable professionals, including Silvano Piani and Egidio Marchi. These partnerships have contributed to the advancement of his research and innovations.
Conclusion
Fabrizio Ungarelli's contributions to the field of glycosaminoglycans have led to significant advancements in the development of therapeutic agents. His innovative patents and collaborations highlight his commitment to improving medical treatments and enhancing biological properties.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.