Company Filing History:
Years Active: 2013-2020
Title: Innovations by Fabio Salvatore Palumbo
Introduction
Fabio Salvatore Palumbo is an accomplished inventor based in Trabia, Italy. He has made significant contributions to the field of biomedical engineering, particularly in the development of innovative hydrogels for therapeutic applications. With a total of 5 patents to his name, Palumbo's work focuses on enhancing treatment options for conditions such as celiac disease.
Latest Patents
Palumbo's latest patents include groundbreaking inventions related to hydrogels derived from methacrylic hyaluronic acid derivatives. One notable patent describes a composition comprising hydrogels loaded with exogenous enzymes, specifically prolyl endopeptidase (PEP) and endoprotease (EP), intended for the oral treatment of celiac disease. This invention outlines a one-pot methodology for preparing methacrylic derivatives of hyaluronic acid, which involves the formation of an active group on hydroxyl groups, followed by substitution with ethylenediamine and reaction with methacrylic anhydride. The resulting methacrylic hyaluronic acid derivatives are utilized to create hydrogels that effectively release enzymes in simulated gastrointestinal fluids.
Another patent details a two-step procedure for producing functionalized hyaluronic acid derivatives. This process involves inserting functional groups into hyaluronic acid through the formation of a specific active group in an organic solvent, followed by nucleophilic substitution. The derivatives produced can be further functionalized to create photocrosslinkable hydrogels, expanding their potential applications in medical treatments.
Career Highlights
Throughout his career, Palumbo has worked with various companies, including Mero S.r.l. and Novagenit S.r.l. His expertise in the field has allowed him to develop innovative solutions that address critical health challenges.
Collaborations
Palumbo has collaborated with notable colleagues such as Gaetano Giammona and Giovanna Pitarresi. Their combined efforts have contributed to the advancement of research in the field of biomedical applications.
Conclusion
Fabio Salvatore Palumbo's innovative work in the development of hydrogels for therapeutic use showcases his dedication to improving health outcomes. His patents reflect a commitment to advancing medical technology and providing effective solutions for patients.