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Title: F Andrew Ray: Innovator in Chromosomal Characterization
Introduction
F Andrew Ray is a notable inventor based in Fort Collins, CO (US). He has made significant contributions to the field of genetics, particularly in the characterization of chromosomal inversions. With a total of 4 patents, his work has advanced the understanding of chromosomal structures and their implications in genetic research.
Latest Patents
Ray's latest patents include innovative kits and methods for the characterization of chromosomal inversions. One of his patents describes a kit for the characterization of chromosomal inversions using single-stranded probes. This kit allows for the detection of inversions by utilizing reporter species attached to oligonucleotide strands that hybridize to specific portions of sister chromatids prepared by the CO-FISH procedure. If an inversion occurs, the marker probes will be detected on the second sister chromatid at the same location as the inversion on the first chromatid. The kit includes non-repetitive probes that may hybridize to a target DNA sequence of only one DNA strand of one chromatid, along with reagents suitable for performing CO-FISH.
Another patent focuses on a method for characterizing chromosomal inversions using anti-parallel probes. This method also employs reporter species attached to oligonucleotide strands that hybridize to portions of sister chromatids. In this case, one or more reporter species are replaced with anti-parallel probes that hybridize at known locations along the second sister chromatid, allowing for the identification and estimation of the position and size of the inversion.
Career Highlights
Throughout his career, F Andrew Ray has worked with esteemed institutions such as the Colorado State University Research Foundation and the University of Texas System. His research has contributed to advancements in genetic analysis and has been instrumental in developing tools for researchers in the field.
Collaborations
Ray has collaborated with notable colleagues, including Susan M Bailey and Edwin H Goodwin. These partnerships have further enriched his research and innovation in the field of genetics.
Conclusion
F Andrew Ray's contributions to the characterization of chromosomal inversions have made a significant impact in genetic research. His innovative patents and collaborations highlight his dedication to advancing scientific knowledge in this important area.