Ewa Jakobs

Title: Ewa Jakobs: Innovator in Pharmaceutical Chemistry

Introduction

Ewa Jakobs is a notable inventor based in Sopot, Poland. She has made significant contributions to the field of pharmaceutical chemistry, particularly through her innovative work on polyene macrolides. Her research has led to the development of compounds that exhibit high pharmacological activity against various fungal infections.

Latest Patents

Ewa Jakobs holds a patent for "Salts of N-glycosyl derivatives of polyene macrolides." This patent describes new compounds, specifically N-methylglucamine salts of N-glycosyl derivatives of polyene macrolides, including amphotericin B, polifungin, and nystatin. These compounds are prepared by reacting an amino group containing polyene macrolide with an aldose or ketose mono- or oligosaccharide in an organic solvent medium. The resulting N-glycosyl derivatives are precipitated from the reaction medium and transformed into N-methylglucamine salts, which are then crystallized from higher alkanols, such as n-butanol. This innovative approach has shown promise in treating topical and systemic fungal infections.

Career Highlights

Ewa Jakobs has worked at prominent institutions, including the Gdańsk University of Technology and the Pharmaceutical Industry Institute. Her experience in these organizations has allowed her to advance her research and contribute to the development of effective pharmaceutical solutions.

Collaborations

Ewa has collaborated with notable colleagues, including Leonard S. Falkowski and Zuzanna Kowszyk-Gindifer. These partnerships have enriched her research and expanded the impact of her work in the pharmaceutical field.

Conclusion

Ewa Jakobs is a pioneering inventor whose work in pharmaceutical chemistry has led to significant advancements in the treatment of fungal infections. Her innovative patents and collaborations highlight her dedication to improving healthcare through scientific research.