Evgeni A Kabotyanski

Title: Evgeni A Kabotyanski: Innovator in Nucleic Acid Analysis

Introduction

Evgeni A Kabotyanski is a notable inventor based in Stony Brook, NY (US). He has made significant contributions to the field of nucleic acid analysis, holding 2 patents that showcase his innovative approach to scientific challenges. His work is primarily associated with the State University of New York, where he continues to advance research in microfluidic systems and capillary electrophoresis.

Latest Patents

One of Kabotyanski's latest patents is titled "Massively parallel 2-dimensional capillary electrophoresis." This invention discloses a highly efficient method, system, and apparatus for nucleic acid analysis, including sequencing. The system is capable of sequencing DNA sizes ranging from fragments to mammalian size genomes, achieving mouse draft quality at a significantly reduced cost. It utilizes a massive parallel capillary electrophoretic separation with two-dimensional monolith multi-capillary arrays (2D-MMCA). The method allows for sequence identification using fluorescent or otherwise labeled dideoxynucleotide-terminated DNA extension products generated by various immobilized colonies of single template molecules. The cost reduction is a notable advantage, achieved through massively parallel sub-nanoliter volume reactions and the increased throughput of the CE separation and detection.

Another significant patent is "Method and device for manipulating liquids in microfluidic systems." This invention relates to microfluidic systems with specially designed components that enhance or reduce capillarity. The methods and devices enable bubble-less dispensing and mixing of small volumes of different liquids, making them suitable for applications such as polymerase chain reaction and capillary electrophoresis.

Career Highlights

Kabotyanski's career is marked by his dedication to advancing the field of nucleic acid analysis. His innovative patents reflect his commitment to improving existing methods and reducing costs in scientific research. His work has the potential to significantly impact various biological applications, enhancing the efficiency and effectiveness of nucleic acid sequencing and analysis.

Collaborations

Throughout his career, Kabotyanski has collaborated with notable colleagues, including Vera Gorfinkel and Boris Gorbovitski. These collaborations have contributed to the development of his innovative technologies and have fostered a collaborative research environment.

Conclusion

Evgeni A Kabotyanski is a distinguished inventor whose work in nucleic acid analysis