Hamburg, Germany

Eva-Marie Mandelkow


Average Co-Inventor Count = 4.5

ph-index = 2

Forward Citations = 4(Granted Patents)


Company Filing History:


Years Active: 2003-2009

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3 patents (USPTO):Explore Patents

Title: Eva-Marie Mandelkow: Innovator in Alzheimer's Disease Research

Introduction

Eva-Marie Mandelkow is a prominent inventor based in Hamburg, Germany. She has made significant contributions to the field of neuroscience, particularly in the study of Alzheimer's disease. With a total of 3 patents, her work focuses on understanding and treating neurodegenerative conditions.

Latest Patents

One of her latest patents is related to a DNA sequence encoding a novel neuronal protein kinase (NPK-110). This invention involves the phosphorylation of tau proteins and other microtubule-associated proteins (MAPs) at crucial binding positions. The patent also covers serine or threonine residues and epitopes phosphorylated by NPK on MAPs, along with antibodies that specifically bind to this protein kinase. The pharmaceutical compositions developed from this invention aim to treat Alzheimer's disease and cancer, including diagnostic kits and methods for detection.

Another significant patent addresses phosphorylated tau protein epitopes associated with Alzheimer's disease. This invention identifies protein kinases responsible for tau protein epitope phosphorylation and includes antibodies specific for these tau epitopes. Additionally, it encompasses pharmaceutical compositions, detection methods, and testing methods for drugs effective in dissolving paired helical filaments linked to Alzheimer's disease.

Career Highlights

Eva-Marie Mandelkow is affiliated with the Max Planck Society for the Advancement of Science, where she conducts her research. Her work has been instrumental in advancing our understanding of the molecular mechanisms underlying Alzheimer's disease.

Collaborations

She has collaborated with notable colleagues, including Eckhard Mandelkow and Jacek Biernat, to further her research efforts.

Conclusion

Eva-Marie Mandelkow's innovative work in the field of Alzheimer's disease research has the potential to lead to significant advancements in diagnosis and treatment. Her contributions are vital in the ongoing battle against neurodegenerative diseases.

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