Eun Sil Sung

Title: Eun Sil Sung: Innovator in Antibody Engineering

Introduction

Eun Sil Sung is a prominent inventor based in Suwon-si, South Korea, known for his significant contributions to the field of antibody engineering. With a total of four patents to his name, his innovations focus on enhancing antibody efficiency and stability, which are crucial for therapeutic applications.

Latest Patents

One of Eun Sil Sung's latest patents is titled "CH3 domain variant pair inducing formation of heterodimer of heavy chain constant region of antibody at high efficiency, method for preparing same, and use thereof." This patent discloses a CH3 domain variant pair of an antibody, along with a method for preparing the variant and its potential applications. The invention highlights how a mutation in the CH3 domain can significantly improve the yield (90 to 95% or more) in creating a heterodimer of the heavy chain constant region of antibodies. This advancement not only offers remarkable heat stability but also leads to the development of bispecific monoclonal antibodies capable of recognizing two distinct antigens concurrently. Such innovations have promising implications for the treatment and prevention of diseases related to specific target antigens.

Career Highlights

Eun Sil Sung is currently affiliated with the Ajou University Industry-Academic Cooperation Foundation, where he continues to advance research in antibody technology. His pioneering work is characterized by a deep understanding of antibody structures and their functionalities, ultimately benefiting therapeutic science.

Collaborations

In his research endeavors, Eun Sil Sung collaborates with notable colleagues, including Yong Sung Kim and Hye Ji Choi. Together, they contribute to the dynamic field of biotechnology, pushing the boundaries of what can be achieved through innovative antibody designs.

Conclusion

Eun Sil Sung's impactful patents and collaborations exemplify his dedication to improving antibody engineering. By enhancing the efficiency and stability of antibodies, his work holds great promise for the development of novel therapies, making significant strides in the medical and pharmaceutical fields. His inventions not only enrich academic knowledge but also pave the way for practical applications that can transform healthcare.