Company Filing History:
Years Active: 1997
Title: Eugenio Garegnani: Innovator in Pharmaceutical Chemistry
Introduction
Eugenio Garegnani is a notable inventor based in Marcallo Con Casone, Italy. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the preparation of antibiotic precursors. With a total of 2 patents to his name, his work has implications for the development of important medicinal compounds.
Latest Patents
Garegnani's latest patents include a process for the preparation of amikacin precursors. This process involves the preparation of a 3,6'-di-N-Acyl-1-[L-(-)-4-Acylamino-2-hydroxybutyryl] kanamycin A. The method comprises reacting kanamycin A with an aluminum salt in an inert organic solvent. The aluminum complex obtained is treated with a N-acylating agent, followed by acidification of the reaction mixture. The process also includes isolating the 3,6'-di-N-Acyl-kanamycin A and treating the protonated form with an active derivative of L-(-)-4-Acyl-amino-2-hydroxybutyric acid. The final product is isolated by correcting the pH.
Career Highlights
Eugenio Garegnani is associated with Biochimica Opos Spa, where he continues to innovate in the pharmaceutical sector. His expertise in chemical processes has positioned him as a valuable asset in the development of new antibiotic formulations.
Collaborations
Garegnani collaborates with Leone Dall'Asta, contributing to advancements in their shared field of research.
Conclusion
Eugenio Garegnani's work exemplifies the intersection of innovation and pharmaceutical science. His patents reflect a commitment to improving antibiotic production processes, which is crucial for public health.