Eugene Palovcak

Title: Innovations of Eugene Palovcak in Cryo-EM Technology

Introduction

Eugene Palovcak is a notable inventor based in San Francisco, CA (US). He has made significant contributions to the field of cryo-electron microscopy (cryo-EM) through his innovative patent. His work focuses on enhancing the analysis of diverse samples, which is crucial for advancements in various scientific fields.

Latest Patents

Eugene Palovcak holds a patent for "Graphene oxide affinity sample grids for Cryo-EM." This innovation enables facile cryo-EM analysis of diverse samples. The patent describes methods of functionalizing sample grids for cryo-EM, including the creation of high-quality graphene oxide films on cryo-EM substrates. The cryo-EM sample substrates are functionalized with affinity molecules that efficiently concentrate sample molecules and other specimen types on the grid, away from the air-water interface. Affinity groups include amines and proteins, such as tagging system proteins and peptides, which can capture diverse sample types with high affinity. Additionally, spacers like PEG chains are used to position sample particles away from the substrate surface, thereby reducing substrate-induced artifacts. He has 1 patent to his name.

Career Highlights

Eugene Palovcak is affiliated with the University of California, where he continues to contribute to research and innovation in cryo-EM technology. His work has been instrumental in advancing methodologies that improve the quality and efficiency of sample analysis.

Collaborations

Eugene has collaborated with notable colleagues, including Feng Wang and David A Agard. Their combined expertise has furthered the development of innovative solutions in the field of cryo-EM.

Conclusion

Eugene Palovcak's contributions to cryo-EM technology through his innovative patent demonstrate his commitment to advancing scientific research. His work not only enhances the analysis of diverse samples but also paves the way for future innovations in the field.