Etienne Daniel Francois Jacotot

Title: Etienne Daniel Francois Jacotot: Innovator in HIV Research

Introduction

Etienne Daniel Francois Jacotot is a notable inventor based in Paris, France. He has made significant contributions to the field of HIV research, particularly in understanding the interactions of viral proteins with mitochondrial components. With a total of 2 patents, his work has implications for therapeutic strategies against HIV.

Latest Patents

Jacotot's latest patents focus on innovative screening methods for identifying inhibitors of the human immunodeficiency virus (HIV) viral protein R (Vpr) binding to the adenine nucleotide translocator (ANT). The first patent addresses the induction of mitochondrial membrane permeabilization through the interaction of the HIV-1 Vpr protein with ANT. This invention provides reagents and methods for inducing or inhibiting the binding of Vpr to ANT, which is crucial for understanding mitochondrial functions and apoptosis. The second patent similarly explores mimetics and inhibitors of the interaction between Vpr and ANT, further emphasizing the importance of this interaction in HIV pathogenesis.

Career Highlights

Throughout his career, Jacotot has worked with prestigious institutions such as Institut Pasteur and the Institut National de la Santé et de la Recherche Médicale. His research has been pivotal in advancing the understanding of HIV and its effects on cellular mechanisms.

Collaborations

Jacotot has collaborated with esteemed colleagues, including Guido Kroemer and Bernard P. Roques, contributing to a rich exchange of ideas and research findings in the field of virology and cellular biology.

Conclusion

Etienne Daniel Francois Jacotot's innovative work in HIV research highlights the critical intersection of virology and mitochondrial biology. His patents and collaborations continue to influence the scientific community and pave the way for future advancements in therapeutic approaches against HIV.