Errol De Souza

Title: Errol De Souza: Innovator in Insulin Formulations

Introduction

Errol De Souza is a notable inventor based in Cambridge, MA, who has made significant contributions to the field of pharmacology, particularly in the development of insulin formulations. His innovative work focuses on enhancing the efficacy and comfort of insulin delivery for patients with diabetes.

Latest Patents

De Souza holds a patent for "Magnesium compositions for modulating the pharmacokinetics and injection site pain of insulin." This patent describes compositions and methods designed to reduce injection site pain associated with rapid-acting injectable insulin formulations. The formulations include insulin combined with a zinc chelator, such as ethylenediaminetetraacetic acid (EDTA), a dissolution/stabilization agent like citric acid, and a magnesium salt. Additionally, the patent outlines new concentrated insulin formulations and methods to enhance the absorption of existing rapid-acting analog formulations by mixing them with dry powder excipients at the time of administration.

Career Highlights

De Souza's career is marked by his role at Biodel Inc., where he has been instrumental in advancing insulin delivery technologies. His innovative approaches have the potential to significantly improve the quality of life for individuals requiring insulin therapy.

Collaborations

Throughout his career, De Souza has collaborated with esteemed colleagues, including Roderike Pohl and Robert Hauser, contributing to the advancement of insulin formulation technologies.

Conclusion

Errol De Souza's work in the field of insulin formulations exemplifies the impact of innovation on healthcare. His contributions continue to pave the way for improved diabetes management solutions.