Ernö Brücher

Title: Ernö Brücher: Innovator in Medical Chemistry

Introduction

Ernö Brücher is a notable inventor based in Debrecen, Hungary. He has made significant contributions to the field of medical chemistry, particularly in the area of reducing toxic effects associated with gadolinium-based contrast agents.

Latest Patents

Brücher holds a patent for the use of L-Histidine and its derivatives. This invention discloses the application of L-Histidine to reduce gadolinium accumulation in target organs, thereby preventing its toxic effects after the administration of gadolinium-based contrast agents. The invention also addresses the prevention of nephrogenic systemic fibrosis (NSF) syndrome in patients with impaired renal functionality. Additionally, it includes a kit that utilizes L-Histidine to prevent toxicity associated with free Gd3+ through oral administration before the contrast agent is given. The method for preventing toxic metal accumulation involves administering L-Histidine, preferably in a single oral dose ranging from 0.2 to 20 grams.

Career Highlights

Brücher is affiliated with Bracco Imaging S.p.a., where he continues to contribute to advancements in medical imaging and safety. His work has been pivotal in enhancing patient safety during imaging procedures.

Collaborations

He has collaborated with notable colleagues, including Baranyai Zsolt and Simona Bussi, to further research and development in his field.

Conclusion

Ernö Brücher's innovative work in the use of L-Histidine represents a significant advancement in medical chemistry, particularly in improving patient safety during imaging procedures. His contributions continue to impact the medical field positively.