Company Filing History:
Years Active: 2017-2018
Title: Biography of Ernie Hiatt
Introduction: Ernie Hiatt is an innovative inventor based in Maceo, Kentucky. He has made significant contributions to the field of bioprocessing, particularly in the production of recombinant enzymes.
Latest Patents: Hiatt holds two patents, with his latest focusing on plant-based recombinant butyrylcholinesterase production methods. This invention provides a new, reliable, easily scalable, and reproducible method for producing recombinant butyrylcholinesterase (rBuChE). By utilizing a plant transfection procedure, various plant strains can generate effective and scalable amounts of rBuChE under acceptable manufacturing processes. This method ensures reliable levels of enzymes for nerve agent protection requirements, including tetrameric products. Engineered plant lines have demonstrated suitable production of these enzymes in tetramer form, with glycan formation and sialylation for optimal potency against organophosphorus agent exposure.
Career Highlights: Hiatt is associated with Kentucky Bioprocessing, Inc., where he has been instrumental in advancing bioprocessing technologies. His work has focused on developing methods that enhance the production of essential enzymes for various applications.
Collaborations: Throughout his career, Hiatt has collaborated with notable coworkers, including Greg Pogue and Romy Kandzia. These partnerships have contributed to the success of his innovative projects and the advancement of bioprocess