Company Filing History:
Years Active: 1990
Title: The Innovative Contributions of Ernestine Mandler
Introduction
Ernestine Mandler is a notable inventor based in Beer-Sheva, Israel. She has made significant contributions to the field of chemical manufacturing, particularly in the production of diazinon, a widely used pesticide. Her innovative approach has led to advancements in the efficiency and safety of this chemical process.
Latest Patents
Mandler holds a patent for a process for manufacturing diazinon. This improved method allows for the production of diazinon that is substantially free of toxic by-products, achieving high yield and very high purity. The process involves mixing 2-isopropyl-4-methyl-6-hydroxypyrimidine with solid sodium or potassium hydroxide in a ketone or ether solvent at a temperature of about 50-60 degrees Celsius until a homogeneous mixture is formed. Following this, diethylthiophosphoryl chloride is added, and the mixture is maintained at a temperature of 55-80 degrees Celsius until the reaction is complete, resulting in the separation of the diazinon formed. Mandler's patent represents a significant advancement in chemical manufacturing.
Career Highlights
Throughout her career, Ernestine Mandler has been associated with Makhteshim Chemical Works Ltd., where she has applied her expertise in chemical processes. Her work has not only contributed to the company's success but has also had a positive impact on the industry as a whole. Mandler's dedication to innovation and safety in chemical production is evident in her patent and ongoing research.
Collaborations
Mandler has collaborated with her coworker, David Ovadia, to further enhance the research and development efforts at Makhteshim Chemical Works Ltd. Their partnership exemplifies the importance of teamwork in driving innovation within the chemical industry.
Conclusion
Ernestine Mandler's contributions to the field of chemical manufacturing, particularly through her patent for an improved process for diazinon production, highlight her role as a pioneering inventor. Her work continues to influence the industry, promoting safer and more efficient manufacturing practices.