Erik Kruus

Title: The Innovative Contributions of Erik Kruus

Introduction

Erik Kruus is a notable inventor based in Hillsborough, NJ (US), recognized for his significant contributions to the field of personalized medicine and classification technologies. With a total of 14 patents to his name, he has made strides in developing systems and methods that enhance decision-making processes in medical applications.

Latest Patents

One of Erik's latest patents focuses on T-cell receptor repertoire selection prediction with physical model augmented pseudo-labeling for personalized medicine decision making. This invention involves systems and methods for predicting T-cell receptor (TCR)-peptide interaction. The process includes training a deep learning model to predict TCR-peptide interactions by determining a multiple sequence alignment (MSA) for TCR-peptide pair sequences. This is achieved using a dataset of TCR-peptide pair sequences and a sequence analyzer. Additionally, TCR structures and peptide structures are built using the MSA and corresponding structures from a Protein Data Bank (PDB) through a MODELLER. The invention generates an extended TCR-peptide training dataset based on docking energy scores determined by docking peptides to TCRs using physical modeling. TCR-peptide pairs are classified and labeled as positive or negative pairs using pseudo-labels based on the docking energy scores. The deep learning model is iteratively retrained based on the extended dataset and pseudo-labels until convergence.

Another significant patent is a classification apparatus that includes an input unit for receiving user operations, an extraction unit for extracting moving image data, and a display control unit for displaying an icon corresponding to the extracted data. The apparatus also features a movement detection unit to detect icon movement on the screen and a specifying unit to classify the moving image data based on the icon's position.

Career Highlights

Erik has worked with prominent companies such as NEC Corporation and NEC Laboratories America, Inc. His experience in these organizations has contributed to his expertise in developing innovative technologies that address complex challenges in the medical and classification fields.

Collaborations

Throughout his career, Erik has collaborated with talented individuals, including Asim Kadav and Cristian Ungureanu. These partnerships have fostered an environment of innovation and creativity, leading to the development of groundbreaking technologies.

Conclusion

Erik Kruus stands out as a pioneering inventor whose work in personalized medicine and classification technologies has the potential to transform decision-making processes in healthcare.