Location History:
- Heverlee, BE (1992)
- Leuven, BE (1980 - 1995)
- Parklaan, BE (1998)
- Louvain, BE (1983 - 1999)
- Lovenjoel, BE (1997 - 1999)
Company Filing History:
12 out of 16 
4 out of 22 
4 out of 21 
Years Active: 1980-1999
Title: **Innovative Contributions of Erik D De Clercq in Nucleotide Analogues**
Introduction
Erik D De Clercq is a renowned inventor based in Louvain, Belgium, known for his significant contributions in the field of nucleotide analogues. With a remarkable portfolio of 22 patents, he has played an instrumental role in advancing therapeutic options, particularly in antiviral research.
Latest Patents
Among his notable recent patents are those involving N.sup.6-substituted nucleotide analogues and their utilitarian applications. These innovations offer new chemical compounds containing N-6 substituted 2,6-diaminopurine and adenine bases, which have shown potential in producing flame retardants, diagnostic reagents, and therapeutics, especially antivirals. Particularly intriguing is the discovery of previously unknown anti-DNA viral activities found in these compounds upon specific substitutions.
Additionally, De Clercq has developed the invention of 9-(2-phosphonylmethoxyethyl) guanine. This invention addresses the challenges associated with the use of new nucleotide analogues as biologically active compounds. The derivatives presented affect both pyrimidine and purine bases, facilitating their accessibility from heterocylic bases. Some of these compounds demonstrate marked antiviral activity, with potential for transformation into effective antiviral agents through chemical modifications.
Career Highlights
Throughout his career, Erik D De Clercq has collaborated with prestigious institutions such as Stichting Rega Vzw and the Institute of Organic Chemistry and Biochemistry of the Academy of Sciences. His work has laid foundational elements for advancements in antiviral therapies, showcasing the impactful intersection of chemistry and medicine.
Collaborations
De Clercq has worked alongside esteemed colleagues including Antonin Holy and Masanori Baba, fostering collaborations that have contributed to the shared goal of innovation in the realm of medicinal chemistry and virology.
Conclusion
In conclusion, Erik D De Clercq's contributions as an inventor are characterized by his dedication to research and development of nucleotide analogues, which continue to open new avenues in antiviral therapies. His innovative patents and collaborative efforts exemplify the importance of interdisciplinary approaches in addressing complex scientific challenges.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.