Bas-Rhin, France

Eric Jacobs


Average Co-Inventor Count = 9.0

ph-index = 1

Forward Citations = 2(Granted Patents)


Company Filing History:


Years Active: 2000

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1 patent (USPTO):Explore Patents

Title: Eric Jacobs - Innovator in Hepatitis B Vaccine Development

Introduction

Eric Jacobs is a notable inventor based in Bas-Rhin, France. He has made significant contributions to the field of biotechnology, particularly in the development of vaccines for hepatitis B. His innovative work has led to advancements that may improve vaccine efficacy and safety.

Latest Patents

Eric Jacobs holds a patent titled "Antigens and methods therefor." This patent describes a composite particle that includes at least two polypeptides corresponding to all or part of a protein with biological activity related to hepatitis B surface antigens. The composite particle presents at least two antigenic determinants provided by the S-protein, preS2-protein, or preS1-protein. Additionally, the invention includes a modified hepatitis B surface antigen L protein, which can be used alone or incorporated into composite particles. A specific embodiment of the modified L protein (L*) comprises residues 12-52, followed by residues 133-145 and residues 175-400 of the L protein. The composite particle may take the form (L*, S), where S is the S-protein of HBsAg. This innovation aims to enhance the preparation of improved hepatitis B vaccines, particularly through expression in yeasts such as S. cerevisiae and Hansenula polymorpha.

Career Highlights

Eric Jacobs is associated with Smithkline Biologicals, S.A., where he has been instrumental in advancing vaccine technology. His work has been pivotal in the development of new immunogens that could lead to more effective hepatitis B vaccines.

Collaborations

Throughout his career, Eric has collaborated with notable colleagues, including Martin Comberbach and Nigel Harford. These partnerships have contributed to the successful development of innovative solutions in the field of vaccine research.

Conclusion

Eric Jacobs is a distinguished inventor whose work in hepatitis B vaccine development has the potential to significantly impact public health. His innovative approaches and collaborations continue to pave the way for advancements in biotechnology.

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