Company Filing History:
3 out of 4 
1 out of 832,812 Years Active: 2000-2008
Title: Enrico Boldrini: Innovator in Ophthalmic and Antimicrobial Solutions
Introduction
Enrico Boldrini is a notable inventor based in Pisa, Italy, recognized for his contributions to the field of ophthalmic and antimicrobial pharmaceutical compositions. With a total of four patents to his name, Boldrini has made significant strides in developing innovative solutions for medical treatments.
Latest Patents
One of Boldrini's latest patents is an ophthalmic composition containing N-acetyl-cysteine for the treatment of dry-eye syndrome. This composition features acetylcysteine as the active ingredient, which has a mucolitic action suitable for administration in eyedrops. The formulation is designed to maintain pH levels between 6.0 and 7.5 and has a physiologically acceptable osmolarity of less than 320 mOsm/kg. The neutralizing agent used does not negatively affect the osmolarity, allowing the product to be isotonic or hypotonic, thus minimizing irritative effects associated with previous formulations.
Another significant patent involves bioadhesive complexes of polycarbophil and azole antifungal or antiprotozoal drugs. These mucoadhesive antimicrobial complexes are created using a cross-linked polyacrylic acid with bioadhesive properties, combined with an imidazole or triazole derivative. The resulting formulations are particularly effective for the topical treatment of mucosal affections and are designed for sustained release antifungal applications.
Career Highlights
Throughout his career, Enrico Boldrini has worked with various companies, including Farmigea S.p.a. His work has focused on developing innovative pharmaceutical solutions that address specific medical needs, particularly in ophthalmology and antimicrobial treatments.
Collaborations
Boldrini has collaborated with notable professionals in his field, including Marco Fabrizio Saettone and Boris Giannaccini. These collaborations have contributed to the advancement of his research and the successful development of his patented inventions.
Conclusion
Enrico Boldrini's innovative work in ophthalmic and antimicrobial compositions showcases his commitment to improving medical treatments. His patents reflect a deep understanding of pharmaceutical science and a dedication to enhancing patient care.