The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 22, 2008
Filed:
Jul. 22, 2002
Enrico Boldrini, Pisa, IT;
Marco Fabrizio Saettone, Pisa, IT;
Patrizia Chetoni, Pisa, IT;
Susi Burgalassi, Pisa, IT;
Boris Giannaccini, Pisa, IT;
Enrico Boldrini, Pisa, IT;
Marco Fabrizio Saettone, Pisa, IT;
Patrizia Chetoni, Pisa, IT;
Susi Burgalassi, Pisa, IT;
Boris Giannaccini, Pisa, IT;
Farmigea S.p.A., Pisa, IT;
Abstract
An ophthalmic pharmaceutical composition containing acetylcysteine as the active ingredient having a mucolitic action, suitable for administration in eyedrops, where N-acetyl-cysteine is neutralised with base DEAE-dextrane in order to reach pH levels preferably between 6.0 and 7.5, and having a physiologically acceptable osmolarity less than 320 mOsm/kg. The presence of a neutralising agent for N-acetyl-cysteine that does not negatively affect the composition osmolarity allows the formulation to be isotonic or even hypotonic, thus avoiding the irritative and potentially damaging effects of previous ophthalmic products containing N-acetyl-cysteine.