Location History:
- La Jolla, CA (US) (1993)
- Strasbourg, FR (2000 - 2001)
- Strosbourg, FR (2001)
Company Filing History:
Years Active: 1993-2001
Title: Innovations of Emmanuel Pitsinos in Nanostructure Development
Introduction
Emmanuel Pitsinos is a notable inventor based in Strasbourg, France. He has made significant contributions to the field of nanotechnology, particularly in the development of self-assembled taxo-diterpenoid nanostructures. With a total of 4 patents to his name, his work has implications for drug solubility and delivery systems.
Latest Patents
Pitsinos' latest patents focus on innovative methods for creating water-soluble nanostructures. One of his key inventions involves onium salts of taxo-diterpenoid-C,,2-O-aza-arenes, which form self-assembling nanostructures above a critical aggregation concentration. These onium salts enhance the solubility of taxo-diterpenoids in water and promote the formation of structures such as helical fibular and spherical micellular forms. Additionally, these compounds serve as water-soluble prodrugs, exemplified by taxol-2′-methylpyridinium tosylate (MPT), which exhibits elevated aqueous solubility and rapid activation by serum proteins.
Another significant aspect of his work is the cyclic chemical switching method for solubilizing and desolubilizing taxo-diterpenoids. This method utilizes 2-halogenated onium salts of aza-arenes to modify the solubility of taxo-diterpenoids in aqueous solvents. The innovative approach allows for a one-step derivatization process, leading to the creation of bioactive taxo-diterpenoid intermediates.
Career Highlights
Emmanuel Pitsinos is affiliated with The Scripps Research Institute, where he continues to advance his research in nanotechnology and drug delivery systems. His work has garnered attention for its potential applications in improving the efficacy of existing drugs and developing new therapeutic agents.
Collaborations
Pitsinos has collaborated with notable colleagues such as Wolfgang Wrasidlo and Rodney K Guy, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Emmanuel Pitsinos is a pioneering inventor whose work in nanostructure development has the potential to revolutionize drug solubility and delivery. His innovative patents and collaborations highlight his significant contributions to the field of
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.