Company Filing History:
3 out of 118 
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1 out of 1,309 
Years Active: 2001-2006
Title: Emir Duzic: Innovator in G-Protein Signaling and Transcriptional Regulation
Introduction
Emir Duzic is a notable inventor based in Nanuet, NY (US), recognized for his contributions to the field of molecular biology. He holds a total of 5 patents that focus on innovative approaches to understanding G-protein signaling and transcriptional regulation.
Latest Patents
Duzic's latest patents include significant advancements in AGS proteins and nucleic acid molecules. One of his key inventions is a screening assay in yeast that identifies G-protein coupled-receptor independent activators and inhibitors of the pheromone pathway using a mammalian cDNA library. His work on Novel Activator of G protein Signaling (AGS) proteins reveals Ras-related proteins that stimulate G protein activity in a receptor-independent manner. Additionally, he has developed isolated AGS fusion proteins, antigenic peptides, and anti-AGS antibodies. His inventions also encompass isolated AGS nucleic acid molecules, recombinant expression vectors, and non-human transgenic animals with introduced or disrupted AGS genes. Furthermore, he has provided diagnostic, screening, and therapeutic methods utilizing these compositions.
Another significant patent focuses on the transcriptional regulation of the human β3-adrenergic receptor gene. Duzic identified regulatory elements responsible for tissue-specific transcriptional regulation, particularly a region in the proximal promoter that contains sequences acting synergistically to achieve full transcriptional activity. His findings have implications for high-throughput assays, such as reporter gene assays, to identify compounds that can enhance β-AR expression.
Career Highlights
Throughout his career, Emir Duzic has worked with prominent companies, including Osi Pharmaceuticals, Inc. and American Home Products Corporation. His experience in these organizations has contributed to his expertise in the field of molecular biology and patent development.
Collaborations
Duzic has collaborated with notable colleagues, including Mary Cismowski and Vedrana S Susulic, which has further enriched his research and innovation endeavors.
Conclusion
Emir Duzic's work in the field of molecular biology, particularly in G-protein signaling and transcriptional regulation, showcases his innovative spirit and dedication to advancing scientific knowledge. His contributions through patents and collaborations highlight his significant impact on the industry.