Company Filing History:
Years Active: 2008
Title: Innovations by Emi Nakashima in Vascular Research
Introduction
Emi Nakashima, an inventive mind based in Tokyo, Japan, has made significant contributions to the field of vascular research. With her ground-breaking work, she developed an immortalized vascular adventitial cell line that promises advancements in medical research and applications.
Latest Patents
Emi Nakashima holds a patent for an "Immortalized Vascular Adventitial Cell Line." The invention aims to provide an immortalized capillary pericyte line that maintains the original function and properties of the cell line derived from tissue. This innovative establishment method allows for the screening of useful substances using the immortalized capillary pericyte line. The process involves homogenizing the cerebral tissue of a transgenic rat engineered with the large T antigen gene of the SV40 thermo-sensitive mutant line tsA58. Subsequently, brain capillaries are treated with protease, leading to subcultured brain capillary cells that establish an immortalized cell expressing SV40 thermo-sensitive large T antigen, PDGF receptor β, and Angiopoietin-1. A remarkable feature of this vascular pericyte line is its ability to deposit calcium on matrix through dense culture.
Career Highlights
Currently, Emi Nakashima is associated with the Japan Science and Technology Agency, contributing to cutting-edge vascular research. Her innovative thinking and dedication to her work have positioned her as a prominent figure in her field.
Collaborations
Emi has collaborated with notable colleagues, including Hisashi Iizasa and Kenji Hattori. These partnerships have further enriched her research, facilitating advancements in the understanding and application of vascular cell lines.
Conclusion
Emi Nakashima's contributions to vascular research through her innovative patent embody the spirit of advancement in science. Her work at the Japan Science and Technology Agency and collaborations with fellow researchers highlight the importance of teamwork in pushing the boundaries of our understanding in the realm of vascular biology.