Company Filing History:
Years Active: 2001-2004
Title: Emi Nagoshi: Innovator in Phage Research
Introduction
Emi Nagoshi is a prominent inventor based in Osaka, Japan. She has made significant contributions to the field of phage research, particularly in the development of phages with nuclear localization signals. With a total of 3 patents to her name, her work has garnered attention in the scientific community.
Latest Patents
One of her latest patents involves the creation of a λ phage with a nuclear localization signal. This innovation was achieved by constructing a vector capable of expressing a fused protein between a gpD protein, which constitutes the head of the λ phage, and a nuclear localization signal sequence. The process included transforming the vector and propagating a mutant λ phage that cannot express the gpD protein in the transformant. The resulting λ phage has been confirmed to package λ phage DNAs of 80% and 100% genome sizes. Further analysis revealed that the nuclear localization signal is exposed on the outside of the phage head, allowing for microinjection into cells to assess its nuclear localization activity. This research has clarified the nuclear localization activity of the phage.
Career Highlights
Emi Nagoshi is currently employed at Dna Vec Research Inc., where she continues to advance her research in phage technology. Her innovative work has positioned her as a key figure in her field.
Collaborations
She collaborates with notable colleagues, including Mahito Nakanishi and Teruo Akuta, who contribute to her research endeavors.
Conclusion
Emi Nagoshi's contributions to phage research, particularly her work on nuclear localization signals, highlight her innovative spirit and dedication to advancing scientific knowledge. Her patents reflect her commitment to exploring new frontiers in biotechnology.