Company Filing History:
Years Active: 1998-2003
Title: Els Robanus Maandag: Innovator in Gene Targeting Technologies
Introduction
Els Robanus Maandag is a prominent inventor based in Haarlem, Netherlands. She has made significant contributions to the field of genetic engineering, particularly in the area of gene targeting in animal cells. With a total of 2 patents, her work has paved the way for advancements in genetic modification techniques.
Latest Patents
Maandag’s latest patents include innovative methods for high efficiency gene targeting in mouse embryonic stem cells. The first patent outlines a process that involves constructing a DNA molecule containing desired sequence modifications, which is then introduced into the cell through various methods such as microinjection or electroporation. This method allows for the selection of cells where the desired modifications have been successfully integrated into the genome via homologous recombination.
The second patent focuses on gene targeting in animal cells using isogenic DNA constructs. Similar to her first patent, this invention also details the construction of a DNA molecule with specific sequence modifications and the introduction of this targeting DNA into the cell. The goal is to achieve precise modifications in the genome, enhancing the potential for genetic research and therapeutic applications.
Career Highlights
Els Robanus Maandag is currently associated with Genpharm International, Inc., where she continues to develop her groundbreaking research. Her work has been instrumental in advancing the methodologies used in genetic engineering, making her a key figure in the field.
Collaborations
Throughout her career, Maandag has collaborated with notable scientists such as Anton J Berns and Hein Te Riele. These partnerships have further enriched her research and contributed to the success of her innovative projects.
Conclusion
Els Robanus Maandag stands out as a leading inventor in the realm of gene targeting technologies. Her contributions have significantly impacted genetic research, and her patents reflect her commitment to advancing the field.
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