Company Filing History:
Years Active: 2015
Title: Elizaveta Sergeyevna Leshchiner (Turkhanova): Innovator in Biodegradable Lipids
Introduction
Elizaveta Sergeyevna Leshchiner (Turkhanova) is a prominent inventor based in Watertown, MA (US). She has made significant contributions to the field of drug delivery systems through her innovative research and development of amine-containing lipids. Her work focuses on creating biodegradable and biocompatible lipids that can effectively deliver therapeutic agents.
Latest Patents
Leshchiner holds a patent for "Amine-containing lipids and uses thereof." This patent describes nitrogen-containing lipids that are prepared from the conjugate addition of amines to acrylates, acrylamides, or other carbon-carbon double bonds conjugated to electron-withdrawing groups. The methods for preparing these lipids from commercially available starting materials are also provided. These amine-containing lipids or their salt forms are particularly suited for use in various drug delivery systems. Given their amino moiety, they are especially effective for delivering polynucleotides. Complexes or nanoparticles containing the inventive lipid and polynucleotide have been prepared, and these lipids may also be utilized in preparing microparticles for drug delivery. They are particularly useful in delivering labile agents due to their ability to buffer the pH of their surroundings.
Career Highlights
Leshchiner is affiliated with the Massachusetts Institute of Technology, where she continues her research and development efforts. Her work has garnered attention for its potential applications in the medical field, particularly in enhancing drug delivery mechanisms.
Collaborations
Some of her notable coworkers include Daniel Griffith Anderson and Andreas Zumbuehl, who have collaborated with her on various research projects.
Conclusion
Elizaveta Sergeyevna Leshchiner (Turkhanova) is a trailblazer in the development of innovative lipids for drug delivery systems. Her contributions to the field are paving the way for advancements in biocompatible and biodegradable therapeutic solutions.