Company Filing History:
Years Active: 2002-2006
Title: Innovations by Elizabeth Jean Seabrook
Introduction
Elizabeth Jean Seabrook is a notable inventor based in Lane Cove, Australia. She has made significant contributions to the field of biotechnology, particularly in the area of biomolecule purification. With a total of 4 patents to her name, her work has advanced methods for isolating and purifying critical biological components.
Latest Patents
One of her latest patents focuses on the separation of Factor VIII. The claims describe methods for isolating functionally active Factor VIII using a membrane-based separation system. This system creates a first and second interstitial volume between at least two restriction membranes. Stabilizing agents are added to the sample and/or an interstitial volume, while a solvent in the first interstitial volume maintains FVIII in a desired charge state. By applying a potential between the first and second interstitial volumes, FVIII is separated on one side of the separation membrane from unwanted molecules on the other side. These methods can also serve as a substitute for one or more steps in conventional purification schemes for separating native or recombinant FVIII.
Another significant patent involves the removal of biological contaminants. This method includes placing a biomolecule and contaminant mixture in a first solvent stream, which is separated from a second solvent stream by an electrophoretic membrane. A buffer with a required pH is selected for the first solvent stream. An electric potential is applied between the two solvent streams, causing the biomolecule to move through the membrane into the second solvent stream while retaining the biological contaminant in the first stream. This process can be adjusted to ensure the desired purity of the biomolecule is achieved.
Career Highlights
Throughout her career, Elizabeth has worked with several companies, including Gradipore Limited and Life Therapeutics Limited. Her innovative approaches have contributed to advancements in the biotechnology sector, particularly in the purification of biomolecules.
Collaborations
Elizabeth has collaborated with notable professionals in her field, including Brendon Conlan and Thomas Norman Turton. These partnerships have further enhanced her research and development efforts.
Conclusion
Elizabeth Jean Seabrook's contributions to biotechnology through her patents and collaborations highlight her role as a leading inventor in the field. Her innovative methods for biomolecule purification continue to impact the industry positively.