This inventor holds 1 USPTO granted patent. Top assignee: Schering Corporation. Active years: 1987.
Company Filing History:
Years Active: 1987
Title: Elijah J Gold: Innovator in Pharmaceutical Chemistry
Introduction
Elijah J Gold is a notable inventor based in West Orange, NJ (US). He has made significant contributions to the field of pharmaceutical chemistry, particularly through his innovative processes in drug synthesis. His work has led to the development of a unique patent that showcases his expertise and creativity in the industry.
Latest Patents
Elijah J Gold holds a patent for the preparation of a specific compound, namely (-)-5-[(R)-1-hydroxy-2-((R)-1-methyl-3-phenyl-propyl)aminoethyl]salicylamide. This multistep process is designed to produce the compound in high yields without the need for chromatography. The process is stereoselective, beginning with the reaction of D-(+)-alpha-methylbenzylamine with benzylacetone. This is followed by the reduction of the resulting Schiff's base to form an amine as an R,R: R,S diastereomeric mixture. The mixture is then resolved to obtain the R,R stereoisomer as a salt, which is converted to a free base. The R,R free base is reacted with an O-protected alpha-bromo-3-carbamoyl-acetophenone to produce the corresponding R,R-ketobenzamide. The final steps involve reduction to yield a mixture of S,R,R;R,R,R hydroxybenzamide, removal of the protecting groups, and resolution of the deprotected product, culminating in the conversion to the free R,R-amine. This innovative approach highlights his ability to streamline complex chemical processes.
Career Highlights
Elijah J Gold has had a distinguished career, primarily working with Schering Corporation. His role at the company has allowed him to focus on advancing pharmaceutical research and development. His innovative contributions have not only enhanced the company's portfolio but have also made a significant impact on the industry as a whole.
Collaborations
Throughout his career, Elijah has collaborated with talented individuals such as Wei K Chang and Esther Babad. These partnerships have fostered a creative environment that has led to groundbreaking advancements in pharmaceutical chemistry.
Conclusion
Elijah J Gold is a prominent figure in the field of pharmaceutical innovation, with a patent that exemplifies his expertise and creativity. His work continues to influence the industry, showcasing the importance of