Location History:
- Givaraim, IL (2003)
- Givataim, IL (2006)
Company Filing History:
Years Active: 2003-2006
Title: Eliezer Falb: A Pioneer in Peptide Coupling Innovations
Introduction
Eliezer Falb, an innovative inventor based in Givataim, Israel, has made significant contributions to the field of peptide synthesis through his groundbreaking research and patented processes. With a total of two patents to his name, Falb's work primarily focuses on the efficient coupling of amino acids using advanced reagents, marking a notable advancement in biochemistry.
Latest Patents
Falb's latest patents detail two key processes involving bis-(trichloromethyl) carbonate, also known as triphosgene. The first process describes the use of this compound as a coupling reagent during the assembly of carbohydrates to peptide chains. This method is particularly effective for challenging couplings with sterically hindered amino acid residues. The innovative aspect of this process lies in its ability to facilitate the derivatization of peptides, achieving a bond formation between a free amine on a peptide and a carbohydrate.
The second patent further explores the utility of triphosgene in peptide synthesis. This process allows for the in situ generation of amino acid chloride from protected amino acids, simplifying the coupling to difficult amino acid residues. This versatile reagent also supports the formation of amide bonds between a free amine on a peptide and a carboxylic acid, making it suitable for various applications, including the coupling of amino acids to solid supports.
Career Highlights
Throughout his career, Eliezer Falb has been affiliated with several esteemed companies in the biotechnology sector. Notably, he has worked with Peptor Limited and Develogen Israel Ltd., where he applied his expertise to further research in peptide synthesis and innovation.
Collaborations
Falb has collaborated with distinguished colleagues, including Tamar Yechezkel and Yoseph Salitra, who have contributed to the development and refinement of his cutting-edge methods in peptide coupling. These professional partnerships underscore the collaborative nature of scientific innovation in the field.
Conclusion
Eliezer Falb's contributions to peptide coupling represent an important step forward in biochemistry and innovation. His inventive processes utilizing bis-(trichloromethyl) carbonate have not only paved the way for more efficient peptide synthesis but have also had a lasting impact on various biotechnological applications. As the field of peptide chemistry continues to evolve, the importance of such innovations remains paramount.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.