This inventor holds 1 USPTO granted patent. Top assignee: The Wistar Institute. Active years: 2002.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2002
Title: **Elena S. Stavridi: Innovating p53 Tetramerization Domains in Philadelphia, PA**
Introduction
Elena S. Stavridi is an innovative inventor based in Philadelphia, PA. With a focus on molecular biology, she has made significant contributions to understanding and modifying p53 tetramerization domains. Her research aims to tackle conditions associated with inappropriate p53 function through her patented inventions.
Latest Patents
Elena holds a patent for "Modified p53 tetramerization domains having hydrophobic amino acid substitutions". This patent describes modified p53 tetramerization domains that do not hetero-oligomerize with native p53 tetramerization domains. The modified domains feature various amino acid substitutions within residues 325 to 355 of human p53, including substitutions such as Leu330 with Phe, Met340 with Phe, and others. Additionally, the patent includes p53 proteins with these modified domains linked to a p53 DNA binding domain, highlighting their potential utility in ameliorating diseases related to dysfunctional p53 activity.
Career Highlights
Elena has dedicated her career to pioneering research at the intersection of molecular genetics and cancer biology. Her work has attracted attention not only for its scientific merit but also for its practical applications in developing therapeutic solutions. Through her patent, she showcases her commitment to scientific innovation and advancing the field of cancer research.
Collaborations
Elena collaborates with Thanos D. Halazonetis, a prominent figure in the study of p53 and its implications in cancer biology. Their partnership at The Wistar Institute of Anatomy & Biology emphasizes the institution's role in fostering innovative research, allowing both to contribute significantly to understanding p53's function and its modifications.
Conclusion
Elena S. Stavridi's contributions through her patent are a testament to her innovative spirit and dedication to improving therapeutic approaches for diseases linked to p53 dysfunction. As part of the vibrant research community at The Wistar Institute, her work continues to inspire advancements in molecular biology and cancer research.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile