Elena Menichelli

Title: Innovations by Inventor Elena Menichelli in Binding Assays

Introduction

Elena Menichelli is an innovative inventor based in San Diego, California, known for her contributions to the field of binding assays. With two patents to her name, she has developed methods that significantly enhance the detection and measurement of interactions between ligands and target proteins. Her groundbreaking work has implications in biochemical research and drug development.

Latest Patents

Elena's latest patents include sophisticated methods for measuring binding and cellular engagement of ligands with target proteins. One notable patent outlines a method for detecting and quantitatively measuring the binding properties of compounds to target macromolecules, which are linked to labeling peptides. This method allows for the detection of signals from labeling peptides post-binding, enabling researchers to differentiate between denatured and non-denatured target macromolecules. This differential aids in identifying compounds that bind specifically to the target macromolecules, thus advancing drug discovery.

Another significant patent covers a homogeneous thermal shift ligand binding assay. Similar to her other method, this assay quantitatively measures binding properties of compounds with target macromolecules. Through the use of a chimeric molecule linking target macromolecules to a labeling peptide, this method also assesses the binding affinity, providing critical data for biochemical studies and therapeutic applications.

Career Highlights

Elena has built her expertise through valuable experience at Eurofins DiscoverX Corporation and DiscoverX Corporation. Her roles in these organizations have enabled her to refine her skills in developing innovative technologies that bridge the gap between basic research and practical applications in the pharmaceutical industry.

Collaborations

Throughout her career, Elena has collaborated with several professionals, including her coworker Daniel Kelly Treiber. These partnerships have fostered rich exchanges of ideas and techniques, further enhancing the quality of her inventions and the impact of her work in the scientific community.

Conclusion

Elena Menichelli stands out as a pioneering inventor whose methods promise to revolutionize the way researchers measure and understand ligand-target interactions. Her patents not only reflect her technical skill but also her commitment to advancing scientific knowledge. As she continues her work, her innovations will undoubtedly pave the way for new discoveries and improvements in various biomedical applications.