Egbert Bakker

Title: Egbert Bakker: Innovator in Genetic Diagnostics

Introduction

Egbert Bakker is a prominent inventor based in Leiden, Netherlands. He has made significant contributions to the field of human genetics, particularly in the area of cancer predisposition testing. With a total of 2 patents, his work focuses on the detection of genetic mutations that can lead to breast and ovarian cancer.

Latest Patents

One of Bakker's latest patents is a diagnostic test kit designed to determine a predisposition for breast and ovarian cancer. This invention relates to the detection of specific germline mutations in the BRCA1 gene, which are known to increase the risk of these cancers. The patent also explores the molecular genetic mechanisms that may have contributed to the development of these mutations, particularly the role of Alu repetitive DNA elements found in the intronic regions of the BRCA1 gene. Furthermore, the invention addresses somatic mutations in the BRCA1 gene and their implications for the diagnosis and prognosis of breast and ovarian cancer.

Career Highlights

Bakker is affiliated with Rijksuniversiteit Te Leiden, where he continues to advance research in genetics and cancer diagnostics. His work has been instrumental in enhancing the understanding of inherited predispositions to cancer, thereby contributing to improved diagnostic methods.

Collaborations

Throughout his career, Bakker has collaborated with notable colleagues, including Garrit-Jan Boudewijn Van Ommen and Anne Petrij-Bos. These collaborations have further enriched his research and innovation in the field of genetics.

Conclusion

Egbert Bakker's contributions to genetic diagnostics, particularly in relation to breast and ovarian cancer, highlight the importance of innovation in medical research. His patents and ongoing work continue to pave the way for advancements in cancer detection and prevention.